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Dr. Ariel Waisman

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In 2012 Ariel Waisman obtained his Master’s degree in Biological Sciences from the School of Exact and Natural Sciences of the University of Buenos Aires. He completed his PhD at IQUIBICEN, FCEyN, UBA under the direction of Dr. Alejandra Guberman, investigating the role of the cell cycle in maintaining and changing the identity of pluripotent stem cells. He did part of his doctorate at the Rockefeller University Molecular Embryology Laboratory, New York. After obtaining his PhD in 2017, he began his post-doctorate under the direction of Dr. Santiago Miriuka at FLENI. Ariel also served as a teaching assistant of various subjects at the FCEyN UBA between 2011 and 2017. In 2021 he entered the CONICET Research Career at LIAN-FLENI.

In 2022 he started his independent group in the laboratory where he continues his studies of gene regulatory networks in pluripotent stem cells, cardiac differentiation and regeneration, temporality in embryonic development and placental differentiation.

Student’s training

Current
Ph.D. advisor of Bioing. Joaquín Smucler, CONICET
Ph.D. advisor of Lic. Denisse Saulnier, CONICET
Ph.D. advisor of Lic. Julia Halek, CONICET
Mariana Vera’s current PhD co-director, CONICET

Past
Rodrigo Skop’s UNLP undergraduate thesis advisor.
Juan Puracchio’s undergraduate thesis advisor UADE

Selected publications

The transcription factor OCT6 promotes the dissolution of the naïve pluripotent state by repressing Nanog and activating a formative state gene regulatory network

Ariel Waisman, Federico Sevlever, Denisse Saulnier, Marcos Francia, Renata Blanco, Guadalupe Amín, Antonella Lombardi, Celeste Biani, María Belén Palma, Agustina Scarafía, Joaquín Smucler, Alejandro La Greca, Lucía Moro, Gustavo Sevlever, Alejandra Guberman, Santiago Miriuka

Scientific Reports, 2024


Automatic and unbiased segmentation and quantification of myofibers in skeletal muscle

Ariel Waisman, Alessandra Marie Norris, Martín Elías Costa, Daniel Kopinke

Scientific Reports, 2021


Deep Learning Neural Networks Highly Predict Very Early Onset of Pluripotent Stem Cell Differentiation

Ariel Waisman, Alejandro La Greca, Alan M Möbbs, María Agustina Scarafía, Natalia L Santín Velazque, Gabriel Neiman, Lucía N Moro, Carlos Luzzani, Gustavo E Sevlever, Alejandra S Guberman, Santiago G Miriuka

Stem Cell Reports, 2019


Cell cycle dynamics of mouse embryonic stem cells in the ground state and during transition to formative pluripotency

Ariel Waisman, Federico Sevlever, Martín Elías Costa, María Soledad Cosentino, Santiago G Miriuka, Alejandra C Ventura, Alejandra S Guberman

Scientific Reports, 2019


Inhibition of cell division and DNA replication impair mouse-naive pluripotency exit

Ariel Waisman, Camila Vazquez Echegaray, Claudia Solari, María Soledad Cosentino, Iain Martyn, Alessia Deglincerti, Mohammad Zeeshan Ozair, Albert Ruzo, Lino Barañao, Santiago Miriuka, Ali Brivanlou, Alejandra Guberman

Journal of molecular biology, 2017