The genetic program that controls the maintenance of the properties of human pluripotent stem cells (hCMP) is strictly linked to the regulation of the cell cycle. Although hCMPs exhibit the four canonical phases of the cell cycle (G1, S, G2 […]

CDK5 kinase is a member of the family of cyclin-dependent kinases (CDKs) that, unlike all other members of the family, does not participate directly in cell cycle regulation. Its activity is finely regulated by its interaction with the p35 and […]

Pluripotent stem cells have the potential to differentiate into all the cell types in the adult body. However, there is not a single type of pluripotent cell: during embryonic development, there are different cells that are pluripotent but also show […]