Alzheimer’s disease (AD) the progressive loss of nerve cells causes cognitive impairment and behavioral disorders. Although the adult mammalian brain retains the ability to generate new neurons from neural stem / progenitor cells, these cells are not an abundant or […]

The identification of various genetic susceptibility loci associated with neurodegenerative diseases, such as Frontotemporal Dementia, opens up new possibilities for understanding the pathogenic mechanisms associated with the disease. In this project, we develop induced pluripotent stem cell lines (CMPi) from […]

Gene editing is a genetic engineering technique in which a DNA sequence is modified, deleted or inserted into the genome of any type of living organism. Using this technique, it is possible to study the causes of different diseases and […]